From the Giants’ perspective, though, it doesn’t matter what time they play these games. What matters is winning them.y
Month: September 2025
Thousands gathered in Brooklyn on Sept. 1 to dance before dawn in the annual J’ouvert parade.
Kicking off at Grand Army Plaza in Prospect Park under the cover of darkness, New Yorkers partook in the traditional carnival celebration, which saw legions of revelers march down Flatbush Avenue to Eastern Parkway and along Empire Boulevard.
Rubbing oil and throwing paint and powder at one another, partygoers twirled and frolicked in a rush of color and the dawn light. The oil and paint are meant to symbolize liberation while also defying the colonialism of the past.
Attendees smiled and cheered as they reached out to one another with oil-covered hands, bidding each other good tidings.
White t-shirts became soaked with oil, and faces were smeared with it as well. Steel bands pounded on their pans, filling the quiet streets with music.
J’Ouvert itself stems from the French phrase jour ouvert, meaning daybreak or morning, and marks the traditional start of the West Indian American Day Carnival and Parade, a Labor Day-long lineup of festivities honoring Caribbean culture and a celebration of freedom.
The NYPD made its presence known as it accompanied the J’ouvert revelers with a few officers even getting in on the fun. There were no reports of any major incidents.
The J’Ouvert festivities culminated at Utica Avenue then segued into the West Indian American Day Parade, which began near Lincoln Terrace Park.
The two-mile parade then returned down Eastern Parkway to the Grand Army Plaza and will finish on Monday afternoon at the Brooklyn Museum.
Delirium in elderly as the indication of the medication interactions and side effect – 8.15. – 9.1.25 https://t.co/kwTYA90gsd pic.twitter.com/bx9ig4v7uR
— Michael Novakhov (@mikenov) September 1, 2025
Delirium in elderly as the indication of the medication interactions and side effect
(the case of A.N.)
Side Effects – 8.15.25
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- Polypharmacy: Elderly patients often take multiple medications for various health conditions. Taking five or more medications, a phenomenon known as polypharmacy, is a major risk factor for delirium.
- Changes in metabolism: As people age, the function of the kidneys and liver—the organs that process and eliminate drugs—slows down. This can cause medications to accumulate in the body and lead to higher drug concentrations, increasing the risk of side effects.
- Increased brain sensitivity: The aging brain is more susceptible to medications that affect the central nervous system, such as anesthetics and psychoactive drugs.
- Comorbidities: The presence of multiple illnesses (multimorbidity) can make older adults more vulnerable to drug side effects.
- Examples: Certain antihistamines (like diphenhydramine), tricyclic antidepressants, and some medications for Parkinson’s disease.
- Examples: Diazepam, lorazepam, and alprazolam.
- Examples: Antidepressants, antipsychotics, and anticonvulsants.
- Steroids: Can cause cognitive impairment, with a higher risk in susceptible individuals.
- H2-receptor antagonists: Medications like cimetidine, used for heartburn, have been linked to confusion and delirium.
- Cardiac medications: Digoxin and certain beta-blockers can cause confusion in some elderly patients.
- Identify reversible factors: Delirium is often preventable and reversible, with drugs being one of the most common causes.
- Conduct a medication review: Healthcare professionals, sometimes with the help of a clinical pharmacist, should review the patient’s medication list for potentially harmful drugs, interactions, and inappropriate dosages.
- “Start low and go slow”: This prescribing philosophy is essential for older adults. Using the lowest effective dose and carefully titrating it upwards can minimize side effects.
- Discontinue the offending agent: When a specific drug is identified as the cause, stopping it or finding an alternative is often the primary treatment.
- Polypharmacy: Older adults often take multiple medications for various conditions, increasing the risk of harmful drug interactions. [1, 2]
- Age-Related Changes: Age-related physiological changes in the body can alter how medications are processed and affect the brain, making the elderly more prone to drug-induced delirium. [2, 4]
- Comorbidities: The presence of multiple diseases (comorbidities) also raises the risk of developing delirium. [1]
- Anticholinergics: Medications with anticholinergic properties are frequently associated with delirium. [4, 6]
- Opioids and Sedatives: Narcotic pain relievers and other sedatives can trigger delirium. [3, 7]
- Benzodiazepines: These anxiety-reducing medications are known causes of drug-induced delirium. [3, 4]
- Antidepressants: Certain antidepressants can increase the risk. [3, 6]
- Diuretics: Diuretics, especially when combined with other drugs, have been linked to delirium. [1, 6]
- Thorough Medication History: Obtain a comprehensive list of all medications, including over-the-counter drugs and supplements. [2, 3, 8, 9, 10]
- Baseline Mental Status: Determine the patient’s usual mental function before the onset of symptoms to distinguish delirium from other conditions like dementia. [5]
- Focus on Reversible Factors: Drugs are a common and reversible cause of delirium, so identifying and removing the offending medication is a priority for treatment. [4]
- Medication Review: Engage a clinical pharmacist or geriatrician to perform a detailed medication review, as they have expertise in drug interactions and side effects. [1, 11]
- Dose Optimization: In cases of drug-induced delirium, adjusting dosages or changing to alternative medications can help resolve the condition. [4, 12, 13, 14]
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Delirium in an elderly person can be a major indicator of adverse drug side effects and dangerous medication interactions
. Age-related physiological changes increase the risk of these issues, which can disrupt brain function and trigger a confused mental state.
Why medication side effects cause delirium in the elderly
The risk of drug-induced delirium is heightened in older adults due to several factors:
Medications with a high risk of causing delirium
Several classes of drugs are commonly linked to delirium in older adults.
Anticholinergics
Anticholinergic drugs block the neurotransmitter acetylcholine, which is crucial for brain functions like attention and memory. Their use is strongly associated with delirium.
Benzodiazepines and sedatives
These central nervous system depressants are designed to treat anxiety and insomnia but can trigger or worsen delirium in older adults.
Opioids
Used to manage pain, opioids like morphine and codeine are known to cause delirium, especially in hospitalized and postoperative patients.
Psychoactive drugs
Many medications that affect brain function can cause delirium as a side effect.
Other medications
A variety of other drugs can cause delirium, especially when used in combination with other risk factors:
Recognizing and managing drug-induced delirium
Because delirium is a medical emergency, its recognition is critical for patient safety.
–
Delirium in elderly as the indication of the medication interactions and side effect
–
Delirium in the elderly can indicate underlying medication interactions or side effects, as polypharmacy (multiple medications) and age-related changes increase their susceptibility. A thorough medication history, review of frequently associated drugs like opioids, benzodiazepines, anticholinergics, and diuretics, and a clinical assessment of the patient’s baseline mental status are crucial for diagnosis and management. Identifying and reversing these drug-induced factors is key to treating delirium in this vulnerable population. [1, 2, 3, 4, 5]
Why Elderly Patients Are More Susceptible
Medications Linked to Delirium
A thorough medication review is vital, as many drug classes can contribute to delirium in older adults. Some common examples include: [4, 6]
Key Steps in Diagnosis and Management
By understanding these factors, healthcare providers can better identify, prevent, and manage drug-induced delirium in elderly patients. [4, 11]
AI responses may include mistakes.
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https://t.co/JIAdwxm8fY
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The South Caucasus News Review https://t.co/KYGCUA0Nwy https://t.co/68VWXDt66g#SouthCaucasus #SouthCaucasusNews#Armenia #Azerbaijan #Georgia
Armenia Azerbaijan Georgia
–https://t.co/DO5LG3PY4Thttps://t.co/O0SIgLVWzM
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News Review – Comprehensive,…— Michael Novakhov (@mikenov) September 1, 2025
The GPS of a plane carrying the president of the European Commission, Ursula von der Leyen, encountered suspected Russian interference while trying to land in Bulgaria, a spokesperson for the Commission told TIME.
“We have received information from Bulgarian authorities that they suspect this blatant interference was carried out by Russia. We are well aware that threats and intimidation are a regular component of Russia’s hostile actions,” said European Commission Deputy Chief Spokesperson Arianna Podestà in an emailed statement, reiterating that the plane landed safely on Sunday despite the GPS jamming.
[time-brightcove not-tgx=”true”]
Per Podestà, the event will only serve to “further reinforce” the European Commission’s “unshakable commitment to ramp up [its] defence capabilities and support for Ukraine.”
A source familiar with the matter told TIME the pilots used paper maps to successfully land the plane.
TIME has reached out to Bulgarian Authorities and the Russian Foreign Ministry regarding the allegations.
A strong ally of Ukrainian President Volodymyr Zelensky, von der Leyen has frequently condemned Russia’s actions against Ukraine following its invasion of the country in 2022.
Last week, she lambasted the Russian strikes that hit the E.U. delegation in Kyiv for the first time, along with the British Council building. “Russia must stop its indiscriminatory attacks on civilian infrastructure immediately and join negotiations for a just and lasting peace,” she urged.
On Sunday, von der Leyen visited an ammunition factory in the Bulgarian town of Sopot, where she said that shells are manufactured for both E.U. and Ukrainian stockpiles and praised the site for benefiting “Europe’s security as a whole.”
Continuing her tour of frontline member states on Monday, von der Leyen visited Lithuania, which borders Russia, and announced an economic roadmap for the next five years is due to be outlined in October to address defence investment regarding the war in Ukraine and Russian threats towards other neighbouring countries.
“You live under geopolitical and economic pressure, as well as constant military and hybrid threats,” said von der Leyen in a joint press conference with Lithuanian President Gitanas Nausėda.
In July, the European Commission announced sanctions against Russian individuals and entities accused of these “hybrid threats,” including one Russian company and two individuals in relation to signal jamming from Kaliningrad, a Russian exclave.
“GNSS signal disruptions in several European countries have been linked to electronic warfare activities from Kaliningrad, including jamming and spoofing of GNSS signals, primarily affecting the Baltic States, and disrupting civil aviation,” read the press release.
Read More: How Putin Brushed Off Trump’s Latest Push for Peace in Ukraine
The latest allegations of Russian interference in GPS systems comes almost three weeks after U.S. President Donald Trump met with Russian President Vladimir Putin in Alaska for a “high-stakes” summit.
The meeting served as the first in-person encounter between the Presidents since 2019, and was intended to foster discussions about a path toward a potential cease-fire. But it ended earlier than expected and, notably, without a deal being reached.
Trump has since met with Zelensky and key European leaders at the White House to discuss possible steps forward, during which he ruled out sending U.S. troops to Ukraine as part of security guarantees.
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